Ulrich Beuers Selected Research

Pruritus (Itching)

1/2021	Fibrates for Itch (FITCH) in Fibrosing Cholangiopathies: A Double-Blind, Randomized, Placebo-Controlled Trial.
1/2021	Reduced spontaneous itch in mouse models of cholestasis.
1/2019	Effect of Plasmapheresis on Cholestatic Pruritus and Autotaxin Activity During Pregnancy.
1/2017	Fibrates for the treatment of cholestatic itch (FITCH): study protocol for a randomized controlled trial.
1/2017	Effect of ileal bile acid transporter inhibitor GSK2330672 on pruritus in primary biliary cholangitis: a double-blind, randomised, placebo-controlled, crossover, phase 2a study.
8/2016	A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis.
7/2016	A systematic approach to the management of cholestatic pruritus in primary biliary cirrhosis.
4/2016	Prognostic and mechanistic potential of progesterone sulfates in intrahepatic cholestasis of pregnancy and pruritus gravidarum.
4/2016	Serum Autotaxin Activity Correlates With Pruritus in Pediatric Cholestatic Disorders.
4/2015	Autotaxin activity has a high accuracy to diagnose intrahepatic cholestasis of pregnancy.

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Ulrich Beuers Research Topics

Disease

39	Cholestasis 11/2021 - 05/2002
28	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2021 - 05/2002
27	Pruritus (Itching) 01/2021 - 09/2002
24	Sclerosing Cholangitis 06/2021 - 09/2002
19	Liver Diseases (Liver Disease) 06/2021 - 05/2002
18	Fibrosis (Cirrhosis) 01/2022 - 11/2002
15	Neoplasms (Cancer) 08/2020 - 07/2007
13	Immunoglobulin G4-Related Disease 12/2021 - 06/2013
13	Intrahepatic Cholestasis of Pregnancy 12/2020 - 02/2004
11	Cholangitis 01/2022 - 01/2009
11	Hepatocellular Carcinoma (Hepatoma) 09/2020 - 06/2002
6	Hyperbilirubinemia 01/2022 - 08/2012
6	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021 - 04/2005
6	Disease Progression 01/2021 - 09/2002
6	Autoimmune Pancreatitis 01/2018 - 03/2014
5	Inflammation (Inflammations) 01/2022 - 01/2016
5	Cholangiocarcinoma 01/2018 - 02/2009
4	progressive familial intrahepatic 1 Cholestasis 01/2021 - 04/2016
4	Infections 01/2018 - 01/2008
3	Body Weight (Weight, Body) 01/2021 - 09/2005
3	End Stage Liver Disease 01/2019 - 06/2014
3	Carcinoma (Carcinomatosis) 11/2015 - 02/2009
3	Autoimmune Diseases (Autoimmune Disease) 01/2013 - 09/2006
3	Autoimmune Hepatitis 01/2013 - 10/2005
2	Dysbiosis 02/2021 - 01/2021
2	Bacterial Infections (Bacterial Infection) 01/2021 - 07/2007
2	Portal Hypertension 01/2021 - 01/2020
2	Acute-On-Chronic Liver Failure 01/2021 - 03/2007
2	Cholelithiasis 12/2020 - 09/2010
2	Fatty Liver 12/2019 - 12/2005
2	Non-alcoholic Fatty Liver Disease 01/2018 - 12/2005
2	Bile Duct Diseases (Bile Duct Disease) 01/2018 - 08/2010
2	Chronic Hepatitis C 01/2017 - 01/2014
2	Necrosis 01/2017 - 06/2010
2	Polycystic liver disease 01/2016 - 10/2015
2	Intrahepatic Cholestasis 01/2016 - 03/2007

Drug/Important Bio-Agent (IBA)

48	Bile Acids and Salts (Bile Acids)IBA 11/2021 - 02/2004
24	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 01/2021 - 09/2002
11	Biomarkers (Surrogate Marker)IBA 01/2020 - 09/2002
10	EnzymesIBA 11/2021 - 12/2006
10	Immunoglobulin G (IgG)IBA 08/2020 - 01/2009
7	Immunoglobulins (Immunoglobulin)IBA 01/2022 - 01/2009
7	BilirubinIBA 01/2022 - 06/2015
7	Opioid Analgesics (Opioids)IBA 07/2014 - 09/2010
6	Alkaline PhosphataseIBA 06/2021 - 09/2009
6	AutoantibodiesIBA 12/2019 - 09/2006
6	lysophosphatidic acidIBA 01/2015 - 09/2010
5	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021 - 01/2003
5	AntibodiesIBA 01/2018 - 09/2008
5	Peptides (Polypeptides)IBA 01/2018 - 11/2010
5	Pharmaceutical PreparationsIBA 01/2016 - 01/2006
4	Hormones (Hormone)IBA 06/2021 - 02/2009
4	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 06/2021 - 10/2012
4	Budesonide (Pulmicort)FDA LinkGeneric 01/2021 - 07/2003
4	Phospholipids (Phosphatides)FDA LinkGeneric 12/2020 - 09/2010
4	Messenger RNA (mRNA)IBA 01/2020 - 01/2006
4	Proteins (Proteins, Gene)FDA Link 01/2016 - 03/2004
4	AnionsIBA 06/2015 - 05/2002
4	Rifampin (Rifampicin)FDA LinkGeneric 01/2014 - 03/2005
3	LipidsIBA 01/2022 - 08/2013
3	Rifaximin (L 105)FDA Link 01/2022 - 01/2020
3	Progesterone FDA LinkGeneric 11/2021 - 02/2011
3	Adenosine Triphosphate (ATP)IBA 12/2020 - 11/2010
3	RNA (Ribonucleic Acid)IBA 08/2020 - 01/2016
3	Glycochenodeoxycholic Acid (Glycochenodeoxycholate)IBA 01/2020 - 01/2009
3	Chloride-Bicarbonate AntiportersIBA 01/2018 - 01/2016
3	Bicarbonates (Hydrogen Carbonate)IBA 01/2018 - 06/2006
3	Transaminases (Aminotransferases)IBA 10/2017 - 05/2007
3	SteroidsIBA 04/2016 - 05/2013
3	Cholestyramine Resin (Questran)FDA LinkGeneric 01/2014 - 09/2005
3	Histamine (Histamine Dihydrochloride)FDA Link 01/2014 - 09/2010
3	Member 11 Subfamily B ATP Binding Cassette TransporterIBA 01/2007 - 02/2004
2	AnnexinsIBA 01/2022 - 01/2018
2	Simvastatin (Zocor)FDA LinkGeneric 01/2022 - 01/2020
2	Protons (Proton)IBA 06/2021 - 01/2018
2	aldaferminIBA 06/2021 - 01/2019
2	Fibric Acids (Fibrates)IBA 01/2021 - 01/2017
2	BezafibrateIBA 01/2021 - 01/2017
2	CholatesIBA 01/2020 - 01/2016
2	Interleukin-8 (Interleukin 8)IBA 11/2019 - 01/2016
2	AntigensIBA 01/2018 - 10/2014
2	myrcludex-BIBA 01/2018 - 11/2017
2	Adenylyl Cyclases (Adenylyl Cyclase)IBA 01/2018 - 01/2017
2	Taurocholic Acid (Sodium Taurocholate)IBA 01/2018 - 11/2010
2	obeticholic acidIBA 01/2018 - 08/2016
2	Immunosuppressive Agents (Immunosuppressants)IBA 01/2018 - 05/2015
2	bile acid binding proteinsIBA 11/2017 - 01/2017
2	Prednisolone (Predate)FDA LinkGeneric 07/2017 - 01/2003
2	Antiviral Agents (Antivirals)IBA 01/2017 - 01/2017
2	InterferonsIBA 01/2017 - 01/2017
2	Chenodeoxycholic Acid (Chenix)FDA Link 01/2017 - 01/2012
2	Galactoside 2-alpha-L-fucosyltransferase (Fucosyltransferase 2)IBA 01/2017 - 06/2015
2	Indicators and Reagents (Reagents)IBA 11/2016 - 04/2016
2	Lysophospholipase (Phospholipase B)IBA 04/2016 - 10/2012
2	Oxidoreductases (Dehydrogenase)IBA 04/2016 - 09/2008
2	1-dodecylpyridoxal (PLD)IBA 01/2016 - 10/2015

Therapy/Procedure

22	Therapeutics 01/2022 - 04/2005
13	Liver Transplantation 11/2019 - 09/2002
4	Transplantation 06/2008 - 11/2002
2	Ligation 01/2018 - 01/2016